Cerebellar Vermis and Midbrain Hypoplasia Upon Conditional Deletion of Chd7 from the Embryonic Mid-Hindbrain Region

Reduced fibroblast growth factor (FGF) signaling from the mid-hindbrain or isthmus organizer (IsO) during early embryonic development results in hypoplasia of the midbrain and cerebellar vermis. We previously reported evidence for reduced Fgf8 expression and FGF signaling in the mid-hindbrain region...

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Detalles Bibliográficos
Autores principales: Donovan, Alex P. A., Yu, Tian, Ellegood, Jacob, Riegman, Kimberley L. H., de Geus, Christa, van Ravenswaaij-Arts, Conny, Fernandes, Cathy, Lerch, Jason P., Basson, M. Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632662/
https://www.ncbi.nlm.nih.gov/pubmed/29046629
http://dx.doi.org/10.3389/fnana.2017.00086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632662/
https://www.ncbi.nlm.nih.gov/pubmed/29046629
http://dx.doi.org/10.3389/fnana.2017.00086

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