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Expression, purification and characterization of hepatitis B virus X protein BH3-like motif-linker-Bcl-x(L) fusion protein for structural studies
Hepatitis B virus X protein (HBx) is a multifunctional protein that interacts directly with many host proteins. For example, HBx interacts with anti-apoptotic proteins, Bcl-2 and Bcl-x(L), through its BH3-like motif, which leads to elevated cytosolic calcium levels, efficient viral DNA replication a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632712/ https://www.ncbi.nlm.nih.gov/pubmed/29114584 http://dx.doi.org/10.1016/j.bbrep.2016.12.006 |