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Expression, purification and characterization of hepatitis B virus X protein BH3-like motif-linker-Bcl-x(L) fusion protein for structural studies

Hepatitis B virus X protein (HBx) is a multifunctional protein that interacts directly with many host proteins. For example, HBx interacts with anti-apoptotic proteins, Bcl-2 and Bcl-x(L), through its BH3-like motif, which leads to elevated cytosolic calcium levels, efficient viral DNA replication a...

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Detalles Bibliográficos
Autores principales:	Kusunoki, Hideki, Tanaka, Toshiyuki, Kohno, Toshiyuki, Kimura, Hirokazu, Hosoda, Kazuo, Wakamatsu, Kaori, Hamaguchi, Isao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632712/ https://www.ncbi.nlm.nih.gov/pubmed/29114584 http://dx.doi.org/10.1016/j.bbrep.2016.12.006

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