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MeCP2 Deficiency in Neuroglia: New Progress in the Pathogenesis of Rett Syndrome

Rett syndrome (RTT) is an X-linked neurodevelopmental disease predominantly caused by mutations of the methyl-CpG-binding protein 2 (MeCP2) gene. Generally, RTT has been attributed to neuron-centric dysfunction. However, increasing evidence has shown that glial abnormalities are also involved in the...

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Detalles Bibliográficos
Autores principales: Jin, Xu-Rui, Chen, Xing-Shu, Xiao, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632713/
https://www.ncbi.nlm.nih.gov/pubmed/29046627
http://dx.doi.org/10.3389/fnmol.2017.00316