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MeCP2 Deficiency in Neuroglia: New Progress in the Pathogenesis of Rett Syndrome
Rett syndrome (RTT) is an X-linked neurodevelopmental disease predominantly caused by mutations of the methyl-CpG-binding protein 2 (MeCP2) gene. Generally, RTT has been attributed to neuron-centric dysfunction. However, increasing evidence has shown that glial abnormalities are also involved in the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632713/ https://www.ncbi.nlm.nih.gov/pubmed/29046627 http://dx.doi.org/10.3389/fnmol.2017.00316 |