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Inactive trans-Sialidase Expression in iTS-null Trypanosoma cruzi Generates Virulent Trypomastigotes

Disclosing virulence factors from pathogens is required to better understand the pathogenic mechanisms involved in their interaction with the host. In the case of Trypanosoma cruzi several molecules are associated with virulence. Among them, the trans-sialidase (TS) has arisen as one of particular r...

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Detalles Bibliográficos
Autores principales: Pascuale, Carla A., Burgos, Juan M., Postan, Miriam, Lantos, Andrés B., Bertelli, Adriano, Campetella, Oscar, Leguizamón, M. Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632715/
https://www.ncbi.nlm.nih.gov/pubmed/29046868
http://dx.doi.org/10.3389/fcimb.2017.00430