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A MEN1 pancreatic neuroendocrine tumour mouse model under temporal control

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterised by occurrence of parathyroid tumours and neuroendocrine tumours (NETs) of the pancreatic islets and anterior pituitary. The MEN1 gene, encoding menin, is a tumour suppressor, but its precise role in initiating...

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Detalles Bibliográficos
Autores principales: Lines, K E, Vas Nunes, R P, Frost, M, Yates, C J, Stevenson, M, Thakker, R V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632719/
https://www.ncbi.nlm.nih.gov/pubmed/28420716
http://dx.doi.org/10.1530/EC-17-0040