Boeravinone B, A Novel Dual Inhibitor of NorA Bacterial Efflux Pump of Staphylococcus aureus and Human P-Glycoprotein, Reduces the Biofilm Formation and Intracellular Invasion of Bacteria

This study elucidated the role of boeravinone B, a NorA multidrug efflux pump inhibitor, in biofilm inhibition. The effects of boeravinone B plus ciprofloxacin, a NorA substrate, were evaluated in NorA-overexpressing, wild-type, and knocked-out Staphylococcus aureus (SA-1199B, SA-1199, and SA-K1758,...

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Detalles Bibliográficos
Autores principales: Singh, Samsher, Kalia, Nitin P., Joshi, Prashant, Kumar, Ajay, Sharma, Parduman R., Kumar, Ashok, Bharate, Sandip B., Khan, Inshad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632727/
https://www.ncbi.nlm.nih.gov/pubmed/29046665
http://dx.doi.org/10.3389/fmicb.2017.01868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632727/
https://www.ncbi.nlm.nih.gov/pubmed/29046665
http://dx.doi.org/10.3389/fmicb.2017.01868

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