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Interpreting T-Cell Cross-reactivity through Structure: Implications for TCR-Based Cancer Immunotherapy

Immunotherapy has become one of the most promising avenues for cancer treatment, making use of the patient’s own immune system to eliminate cancer cells. Clinical trials with T-cell-based immunotherapies have shown dramatic tumor regressions, being effective in multiple cancer types and for many dif...

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Detalles Bibliográficos
Autores principales: Antunes, Dinler A., Rigo, Maurício M., Freitas, Martiela V., Mendes, Marcus F. A., Sinigaglia, Marialva, Lizée, Gregory, Kavraki, Lydia E., Selin, Liisa K., Cornberg, Markus, Vieira, Gustavo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632759/
https://www.ncbi.nlm.nih.gov/pubmed/29046675
http://dx.doi.org/10.3389/fimmu.2017.01210