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Non-linearity of the collagen triple helix in solution and implications for collagen function

Collagen adopts a characteristic supercoiled triple helical conformation which requires a repeating (Xaa-Yaa-Gly)(n) sequence. Despite the abundance of collagen, a combined experimental and atomistic modelling approach has not so far quantitated the degree of flexibility seen experimentally in the s...

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Detalles Bibliográficos
Autores principales: Walker, Kenneth T., Nan, Ruodan, Wright, David W., Gor, Jayesh, Bishop, Anthony C., Makhatadze, George I., Brodsky, Barbara, Perkins, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632799/
https://www.ncbi.nlm.nih.gov/pubmed/28533266
http://dx.doi.org/10.1042/BCJ20170217