Effect of position-specific single-point mutations and biophysical characterization of amyloidogenic peptide fragments identified from lattice corneal dystrophy patients

Corneal stromal dystrophies are a group of genetic disorders that may be caused by mutations in the transforming growth factor β-induced (TGFBI) gene which results in the aggregation and deposition of mutant proteins in various layers of the cornea. The type of amino acid substitution dictates the a...

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Detalles Bibliográficos
Autores principales: Anandalakshmi, Venkatraman, Murugan, Elavazhagan, Leng, Eunice Goh Tze, Ting, Lim Wei, Chaurasia, Shyam S., Yamazaki, Toshio, Nagashima, Toshio, George, Benjamin Lawrence, Peh, Gary Swee Lim, Pervushin, Konstantin, Lakshminarayanan, Rajamani, Mehta, Jodhbir S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632800/
https://www.ncbi.nlm.nih.gov/pubmed/28381645
http://dx.doi.org/10.1042/BCJ20170125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632800/
https://www.ncbi.nlm.nih.gov/pubmed/28381645
http://dx.doi.org/10.1042/BCJ20170125

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