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Stereochemistry and biological activity of chlorinated lipids: a study of danicalipin A and selected diastereomers

The syntheses of (+)-16-epi- and (+)-11,15-di-epi-danicalipin A (2 and 3) are reported. The conformations of the parent diols 5 and 6 as well as the corresponding disulfates 2 and 3 were determined on the basis of J-based configuration analysis and supported by calculations. The impact of configurat...

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Detalles Bibliográficos
Autores principales: Boshkow, J., Fischer, S., Bailey, A. M., Wolfrum, S., Carreira, E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632803/
https://www.ncbi.nlm.nih.gov/pubmed/29147515
http://dx.doi.org/10.1039/c7sc03124f