Identification of Potent Chloride Intracellular Channel Protein 1 Inhibitors from Traditional Chinese Medicine through Structure-Based Virtual Screening and Molecular Dynamics Analysis

Chloride intracellular channel 1 (CLIC1) is involved in the development of most aggressive human tumors, including gastric, colon, lung, liver, and glioblastoma cancers. It has become an attractive new therapeutic target for several types of cancer. In this work, we aim to identify natural products...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Wan, Minghui, Liao, Dongjiang, Peng, Guilin, Xu, Xin, Yin, Weiqiang, Guo, Guixin, Jiang, Funeng, Zhong, Weide, He, Jianxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632872/
https://www.ncbi.nlm.nih.gov/pubmed/29147652
http://dx.doi.org/10.1155/2017/4751780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632872/
https://www.ncbi.nlm.nih.gov/pubmed/29147652
http://dx.doi.org/10.1155/2017/4751780

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