Inflammatory activation of human cardiac fibroblasts leads to altered calcium signaling, decreased connexin 43 expression and increased glutamate secretion

Cardiac fibroblasts, which are abundant in heart tissue, are involved not only in extracellular matrix homeostasis and repair, but also in cardiac remodeling after a myocardial infarction that, in turn, can lead to loss of cardiac function and heart failure. Ca(2+) signaling is functionally importan...

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Detalles Bibliográficos
Autores principales: Skiöldebrand, Eva, Lundqvist, Annika, Björklund, Ulrika, Sandstedt, Mikael, Lindahl, Anders, Hansson, Elisabeth, Hultén, Lillemor Mattsson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633159/
https://www.ncbi.nlm.nih.gov/pubmed/29022008
http://dx.doi.org/10.1016/j.heliyon.2017.e00406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633159/
https://www.ncbi.nlm.nih.gov/pubmed/29022008
http://dx.doi.org/10.1016/j.heliyon.2017.e00406

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