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Behavioral testing of minipigs transgenic for the Huntington gene—A three-year observational study
BACKGROUND: Large animal models of Huntington’s disease (HD) may increase the reliability of translating preclinical findings to humans. Long live expectancy offers opportunities particularly for disease modifying approaches, but also challenges. The transgenic (tg) HD minipig model assessed in this...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633197/ https://www.ncbi.nlm.nih.gov/pubmed/29016656 http://dx.doi.org/10.1371/journal.pone.0185970 |