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Behavioral testing of minipigs transgenic for the Huntington gene—A three-year observational study

BACKGROUND: Large animal models of Huntington’s disease (HD) may increase the reliability of translating preclinical findings to humans. Long live expectancy offers opportunities particularly for disease modifying approaches, but also challenges. The transgenic (tg) HD minipig model assessed in this...

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Detalles Bibliográficos
Autores principales:	Schuldenzucker, Verena, Schubert, Robin, Muratori, Lisa M., Freisfeld, Frauke, Rieke, Lorena, Matheis, Tamara, Schramke, Sarah, Motlik, Jan, Kemper, Nicole, Radespiel, Ute, Reilmann, Ralf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633197/ https://www.ncbi.nlm.nih.gov/pubmed/29016656 http://dx.doi.org/10.1371/journal.pone.0185970

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