Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology

Interleukin-6 is a pleiotropic, pro-inflammatory cytokine that can promote both innate and adaptive immune responses. In humans with respiratory virus infections, such as Respiratory Syncytial Virus (RSV), elevated concentrations of IL-6 are associated with more severe disease. In contrast the polym...

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Detalles Bibliográficos
Autores principales: Pyle, Chloe J., Uwadiae, Faith I., Swieboda, David P., Harker, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633202/
https://www.ncbi.nlm.nih.gov/pubmed/28953978
http://dx.doi.org/10.1371/journal.ppat.1006640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633202/
https://www.ncbi.nlm.nih.gov/pubmed/28953978
http://dx.doi.org/10.1371/journal.ppat.1006640

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