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Quantifying the effects of antiangiogenic and chemotherapy drug combinations on drug delivery and treatment efficacy
Tumor-induced angiogenesis leads to the development of leaky tumor vessels devoid of structural and morphological integrity. Due to angiogenesis, elevated interstitial fluid pressure (IFP) and low blood perfusion emerge as common properties of the tumor microenvironment that act as barriers for drug...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633204/ https://www.ncbi.nlm.nih.gov/pubmed/28922358 http://dx.doi.org/10.1371/journal.pcbi.1005724 |