An acquired mechanism of antifungal drug resistance simultaneously enables Candida albicans to escape from intrinsic host defenses

The opportunistic fungal pathogen Candida albicans frequently produces genetically altered variants to adapt to environmental changes and new host niches in the course of its life-long association with the human host. Gain-of-function mutations in zinc cluster transcription factors, which result in...

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Detalles Bibliográficos
Autores principales: Hampe, Irene A. I., Friedman, Justin, Edgerton, Mira, Morschhäuser, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633205/
https://www.ncbi.nlm.nih.gov/pubmed/28953977
http://dx.doi.org/10.1371/journal.ppat.1006655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633205/
https://www.ncbi.nlm.nih.gov/pubmed/28953977
http://dx.doi.org/10.1371/journal.ppat.1006655

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