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Detection of Replication Competent Lentivirus Using a qPCR Assay for VSV-G

Lentiviral vectors are a common tool used to introduce new and corrected genes into cell therapy products for treatment of human diseases. Although lentiviral vectors are ideal for delivery and stable integration of genes of interest into the host cell genome, they potentially pose risks to human he...

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Detalles Bibliográficos
Autores principales: Skrdlant, Lindsey M., Armstrong, Randall J., Keidaisch, Brett M., Lorente, Mario F., DiGiusto, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633339/
https://www.ncbi.nlm.nih.gov/pubmed/29034262
http://dx.doi.org/10.1016/j.omtm.2017.09.001