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The AAA protein Msp1 mediates clearance of excess tail-anchored proteins from the peroxisomal membrane

Msp1 is a conserved AAA ATPase in budding yeast localized to mitochondria where it prevents accumulation of mistargeted tail-anchored (TA) proteins, including the peroxisomal TA protein Pex15. Msp1 also resides on peroxisomes but it remains unknown how native TA proteins on mitochondria and peroxiso...

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Detalles Bibliográficos
Autores principales: Weir, Nicholas R, Kamber, Roarke A, Martenson, James S, Denic, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633344/
https://www.ncbi.nlm.nih.gov/pubmed/28906250
http://dx.doi.org/10.7554/eLife.28507