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CISD2 enhances the chemosensitivity of gastric cancer through the enhancement of 5‐FU‐induced apoptosis and the inhibition of autophagy by AKT/mTOR pathway

Gastric cancer (GC) is a prevalent upper gastrointestinal tumor characterized by high morbidity and mortality due to imperfect screening systems and the rapid development of resistance to 5‐fluorouracil (5‐FU). CDGSH iron sulfur domain 2 (CISD2) has been recently regarded as a candidate oncogene in...

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Detalles Bibliográficos
Autores principales: Sun, Yi, Jiang, Yingming, Huang, Jintuan, Chen, Hao, Liao, Yi, Yang, Zuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633556/
https://www.ncbi.nlm.nih.gov/pubmed/28857517
http://dx.doi.org/10.1002/cam4.1169