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PARP-1 and p53 Regulate the Increased Susceptibility to Oxidative Death of Lymphocytes from MCI and AD Patients

Mild cognitive impairment (MCI) is a clinically detectable initial stage of cognitive deterioration with a high conversion rate to dementia. There is increasing evidence that some of the cerebral alterations present in Alzheimer type dementia can be found in peripheral tissues. We have previously sh...

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Detalles Bibliográficos
Autores principales: Salech, Felipe, Ponce, Daniela P., SanMartín, Carol D., Rogers, Nicole K., Chacón, Carlos, Henríquez, Mauricio, Behrens, Maria I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633596/
https://www.ncbi.nlm.nih.gov/pubmed/29051731
http://dx.doi.org/10.3389/fnagi.2017.00310