Design of an enantioselective artificial metallo-hydratase enzyme containing an unnatural metal-binding amino acid

The design of artificial metalloenzymes is a challenging, yet ultimately highly rewarding objective because of the potential for accessing new-to-nature reactions. One of the main challenges is identifying catalytically active substrate–metal cofactor–host geometries. The advent of expanded genetic...

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Detalles Bibliográficos
Autores principales: Drienovská, Ivana, Alonso-Cotchico, Lur, Vidossich, Pietro, Lledós, Agustí, Maréchal, Jean-Didier, Roelfes, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633786/
https://www.ncbi.nlm.nih.gov/pubmed/29081955
http://dx.doi.org/10.1039/c7sc03477f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633786/
https://www.ncbi.nlm.nih.gov/pubmed/29081955
http://dx.doi.org/10.1039/c7sc03477f

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