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Design of an enantioselective artificial metallo-hydratase enzyme containing an unnatural metal-binding amino acid
The design of artificial metalloenzymes is a challenging, yet ultimately highly rewarding objective because of the potential for accessing new-to-nature reactions. One of the main challenges is identifying catalytically active substrate–metal cofactor–host geometries. The advent of expanded genetic...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633786/ https://www.ncbi.nlm.nih.gov/pubmed/29081955 http://dx.doi.org/10.1039/c7sc03477f |