TGF-β Inhibition Improves Oncolytic Herpes Viroimmunotherapy in Murine Models of Rhabdomyosarcoma

Oncolytic viruses are an emerging class of cancer therapeutics that couple cytotoxicity with the induction of an anti-tumor immune response. Host-virus interactions are complex and modulated by a tumor microenvironment whose immunosuppressive activities can limit the effectiveness of cancer immunoth...

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Detalles Bibliográficos
Autores principales: Hutzen, Brian, Chen, Chun-Yu, Wang, Pin-Yi, Sprague, Les, Swain, Hayley M., Love, Julia, Conner, Joe, Boon, Louis, Cripe, Timothy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633823/
https://www.ncbi.nlm.nih.gov/pubmed/29034312
http://dx.doi.org/10.1016/j.omto.2017.09.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633823/
https://www.ncbi.nlm.nih.gov/pubmed/29034312
http://dx.doi.org/10.1016/j.omto.2017.09.001

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