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Improving Visualization and Interpretation of Metabolome-Wide Association Studies: An Application in a Population-Based Cohort Using Untargeted (1)H NMR Metabolic Profiling

[Image: see text] (1)H NMR spectroscopy of biofluids generates reproducible data allowing detection and quantification of small molecules in large population cohorts. Statistical models to analyze such data are now well-established, and the use of univariate metabolome wide association studies (MWAS...

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Detalles Bibliográficos
Autores principales: Castagné, Raphaële, Boulangé, Claire Laurence, Karaman, Ibrahim, Campanella, Gianluca, Santos Ferreira, Diana L., Kaluarachchi, Manuja R., Lehne, Benjamin, Moayyeri, Alireza, Lewis, Matthew R., Spagou, Konstantina, Dona, Anthony C., Evangelos, Vangelis, Tracy, Russell, Greenland, Philip, Lindon, John C., Herrington, David, Ebbels, Timothy M. D., Elliott, Paul, Tzoulaki, Ioanna, Chadeau-Hyam, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633829/
https://www.ncbi.nlm.nih.gov/pubmed/28823158
http://dx.doi.org/10.1021/acs.jproteome.7b00344