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Targeting an Oncolytic Influenza A Virus to Tumor Tissue by Elastase

Oncolytic viruses are currently established as a novel type of immunotherapy. The challenge is to safely target oncolytic viruses to tumors. Previously, we have generated influenza A viruses (IAVs) containing deletions in the viral interferon antagonist. Those deletions have attenuated the virus in...

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Detalles Bibliográficos
Autores principales: Kuznetsova, Irina, Arnold, Tobias, Aschacher, Thomas, Schwager, Cornelia, Hegedus, Balazs, Garay, Tamas, Stukova, Marina, Pisareva, Maria, Pleschka, Stephan, Bergmann, Michael, Egorov, Andrej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633860/
https://www.ncbi.nlm.nih.gov/pubmed/29034314
http://dx.doi.org/10.1016/j.omto.2017.09.002