Control of HIV Infection In Vivo Using Gene Therapy with a Secreted Entry Inhibitor

HIV entry inhibitors are highly effective in controlling virus replication. We have developed a lentiviral vector that expresses a secreted entry inhibitor, soluble CD4 (sCD4), which binds to the HIV envelope glycoproteins and inactivates the virus. We have shown that sCD4 was secreted from gene-mod...

Descripción completa

Detalles Bibliográficos
Autores principales: Falkenhagen, Alexander, Singh, Jastaranpreet, Asad, Sabah, Leontyev, Danila, Read, Stanley, Zúñiga-Pflücker, Juan Carlos, Joshi, Sadhna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633861/
https://www.ncbi.nlm.nih.gov/pubmed/29246292
http://dx.doi.org/10.1016/j.omtn.2017.08.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633861/
https://www.ncbi.nlm.nih.gov/pubmed/29246292
http://dx.doi.org/10.1016/j.omtn.2017.08.017

Ejemplares similares