Cargando…

Clodronate Improves Survival of Transplanted Hoxb8 Myeloid Progenitors with Constitutively Active GMCSFR in Immunocompetent Mice

New methods to produce large numbers of myeloid progenitor cells, precursors to macrophages (MΦs), by maintaining Hoxb8 transcription factor activity(1) has reinvigorated interest in MΦ cell therapies. We generated Hoxb8-dependent myeloid progenitors (HDPs) by transducing lineage-negative bone marro...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Simon, Kivimäe, Saul, Szoka, Francis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633862/
https://www.ncbi.nlm.nih.gov/pubmed/29034260
http://dx.doi.org/10.1016/j.omtm.2017.08.007