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Structurally plastic peptide capsules for synthetic antimicrobial viruses

A conceptual design for artificial antimicrobial viruses is described. The design emulates viral assembly and function to create self-assembling peptide capsules that promote efficient gene delivery and silencing in mammalian cells. Unlike viruses, however, the capsules are antimicrobial, which allo...

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Detalles Bibliográficos
Autores principales: Castelletto, Valeria, de Santis, Emiliana, Alkassem, Hasan, Lamarre, Baptiste, Noble, James E., Ray, Santanu, Bella, Angelo, Burns, Jonathan R., Hoogenboom, Bart W., Ryadnov, Maxim G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633914/
https://www.ncbi.nlm.nih.gov/pubmed/29081944
http://dx.doi.org/10.1039/c5sc03260a