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Cardiomyocyte‐Specific Telomere Shortening is a Distinct Signature of Heart Failure in Humans

BACKGROUND: Telomere defects are thought to play a role in cardiomyopathies, but the specific cell type affected by the disease in human hearts is not yet identified. The aim of this study was to systematically evaluate the cell type specificity of telomere shortening in patients with heart failure...

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Detalles Bibliográficos
Autores principales: Sharifi‐Sanjani, Maryam, Oyster, Nicholas M., Tichy, Elisia D., Bedi, Kenneth C., Harel, Ofer, Margulies, Kenneth B., Mourkioti, Foteini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634248/
https://www.ncbi.nlm.nih.gov/pubmed/28882819
http://dx.doi.org/10.1161/JAHA.116.005086