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MMI‐0100 Inhibits Cardiac Fibrosis in a Mouse Model Overexpressing Cardiac Myosin Binding Protein C

BACKGROUND: Cardiac stress can trigger production of a 40‐kDa peptide fragment derived from the amino terminus of the cardiac myosin‐binding protein C. Cardiac stress, as well as cMyBP‐C mutations, can trigger production of 1 such truncated protein fragment, a 40‐kDa peptide fragment derived from th...

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Detalles Bibliográficos
Autores principales: Meng, Qinghang, Bhandary, Bidur, Osinska, Hanna, James, Jeanne, Xu, Na, Shay‐Winkler, Kritton, Gulick, James, Willis, Monte S., Lander, Cynthia, Robbins, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634300/
https://www.ncbi.nlm.nih.gov/pubmed/28871043
http://dx.doi.org/10.1161/JAHA.117.006590