Retroviral insertional mutagenesis implicates E3 ubiquitin ligase RNF168 in the control of cell proliferation and survival

The E3 ubiquitin ligase RNF168 is a ring finger protein that has been previously identified to play an important regulatory role in the repair of double-strand DNA breaks. In the present study, an unbiased forward genetics functional screen in mouse granulocyte/macrophage progenitor cell line FDCP1...

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Detalles Bibliográficos
Autores principales: Kizilors, Aytug, Pickard, Mark R., Schulte, Cathleen E., Yacqub-Usman, Kiren, McCarthy, Nicola J., Gan, Shu-Uin, Darling, David, Gäken, Joop, Williams, Gwyn T., Farzaneh, Farzin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634340/
https://www.ncbi.nlm.nih.gov/pubmed/28754805
http://dx.doi.org/10.1042/BSR20170843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634340/
https://www.ncbi.nlm.nih.gov/pubmed/28754805
http://dx.doi.org/10.1042/BSR20170843

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