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NMNAT3 is protective against the effects of neonatal cerebral hypoxia‐ischemia

OBJECTIVE: To determine whether the NAD+ biosynthetic protein, nicotinamide mononucleotide adenylyltransferase‐3 (NMNAT3), is a neuroprotective inducible enzyme capable of decreasing cerebral injury after neonatal hypoxia‐ischemia (H‐I) and reducing glutamate receptor‐mediated excitotoxic neurodegen...

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Detalles Bibliográficos
Autores principales: Galindo, Rafael, Banks Greenberg, Marianne, Araki, Toshiyuki, Sasaki, Yo, Mehta, Nehali, Milbrandt, Jeffrey, Holtzman, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634348/
https://www.ncbi.nlm.nih.gov/pubmed/29046881
http://dx.doi.org/10.1002/acn3.450