Selective intrathecal enrichment of G1m1‐positive B cells in multiple sclerosis

Immunoglobulin gamma (IgG) heavy chain genes are associated with susceptibility to multiple sclerosis (MS) and IgG levels in the cerebrospinal fluid (CSF). However, how these variants are implicated in disease mechanisms remains unknown. Here, we show that proliferating plasmablasts expressing the G...

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Detalles Bibliográficos
Autores principales: Lossius, Andreas, Tomescu‐Baciu, Alina, Holmøy, Trygve, Vedeler, Christian A., Røsjø, Egil, Lorentzen, Åslaug R., Casetta, Ilaria, Vartdal, Frode
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634349/
https://www.ncbi.nlm.nih.gov/pubmed/29046884
http://dx.doi.org/10.1002/acn3.451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634349/
https://www.ncbi.nlm.nih.gov/pubmed/29046884
http://dx.doi.org/10.1002/acn3.451

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