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N-terminal gelsolin fragment potentiates TRAIL mediated death in resistant hepatoma cells

TNF-α related apoptosis-inducing ligand (TRAIL) selectively kills tumor cells, without damaging normal cells. TRAIL receptors facilitate induction of apoptosis for selective elimination of malignant cells. However, some cancer cells have developed resistances to TRAIL which limits anticancer potenti...

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Detalles Bibliográficos
Autores principales: Meyer, Keith, Kwon, Young-Chan, Ray, Ratna B., Ray, Ranjit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634413/
https://www.ncbi.nlm.nih.gov/pubmed/28993697
http://dx.doi.org/10.1038/s41598-017-13131-7