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HIV-infected macrophages and microglia that survive acute infection become viral reservoirs by a mechanism involving Bim

While HIV kills most of the cells it infects, a small number of infected cells survive and become latent viral reservoirs, posing a significant barrier to HIV eradication. However, the mechanism by which immune cells resist HIV-induced apoptosis is still incompletely understood. Here, we demonstrate...

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Detalles Bibliográficos
Autores principales: Castellano, Paul, Prevedel, Lisa, Eugenin, Eliseo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634422/
https://www.ncbi.nlm.nih.gov/pubmed/28993666
http://dx.doi.org/10.1038/s41598-017-12758-w