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Quantifying the relative immune cell activation from whole tissue/organ-derived differentially expressed gene data

Evaluation of immune responses in individual immune cell types is important for the development of new medicines. Here, we propose a computational method designated ICEPOP (Immune CEll POPulation) to estimate individual immune cell type responses from bulk tissue and organ samples. The relative gene...

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Detalles Bibliográficos
Autores principales: Wijaya, Edward, Igarashi, Yoshinobu, Nakatsu, Noriyuki, Haseda, Yasunari, Billaud, Joel, Chen, Yi-An, Mizuguchi, Kenji, Yamada, Hiroshi, Ishii, Ken, Aoshi, Taiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634445/
https://www.ncbi.nlm.nih.gov/pubmed/28993694
http://dx.doi.org/10.1038/s41598-017-12970-8