Bone corticalization requires local SOCS3 activity and is promoted by androgen action via interleukin-6

Long bone strength is determined by its outer shell (cortical bone), which forms by coalescence of thin trabeculae at the metaphysis (corticalization), but the factors that control this process are unknown. Here we show that SOCS3-dependent cytokine expression regulates bone corticalization. Young m...

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Detalles Bibliográficos
Autores principales: Cho, Dae-Chul, Brennan, Holly J., Johnson, Rachelle W., Poulton, Ingrid J., Gooi, Jonathan H., Tonkin, Brett A., McGregor, Narelle E., Walker, Emma C., Handelsman, David J., Martin, T. J., Sims, Natalie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634449/
https://www.ncbi.nlm.nih.gov/pubmed/28993616
http://dx.doi.org/10.1038/s41467-017-00920-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634449/
https://www.ncbi.nlm.nih.gov/pubmed/28993616
http://dx.doi.org/10.1038/s41467-017-00920-x

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