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Renal iron accumulation occurs in lupus nephritis and iron chelation delays the onset of albuminuria

Proteins involved in iron homeostasis have been identified as biomarkers for lupus nephritis, a serious complication of systemic lupus erythematosus (SLE). We tested the hypothesis that renal iron accumulation occurs and contributes to renal injury in SLE. Renal non-heme iron levels were increased i...

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Detalles Bibliográficos
Autores principales: Marks, Eileen S., Bonnemaison, Mathilde L., Brusnahan, Susan K., Zhang, Wenting, Fan, Wei, Garrison, Jered C., Boesen, Erika I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634457/
https://www.ncbi.nlm.nih.gov/pubmed/28993663
http://dx.doi.org/10.1038/s41598-017-13029-4