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Usefulness of kidney slices for functional analysis of apical reabsorptive transporters

Kidney plays a key role in the elimination and reabsorption of drugs and nutrients, however in vitro methods to evaluate renal disposition are limited. In the present study, we investigated usefulness of isolated kidney slice, which had been used for transport only at basolateral membrane of tubular...

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Detalles Bibliográficos
Autores principales: Arakawa, Hiroshi, Washio, Ikumi, Matsuoka, Natsumi, Kubo, Hikaru, Staub, Angelina Yukiko, Nakamichi, Noritaka, Ishiguro, Naoki, Kato, Yukio, Nakanishi, Takeo, Tamai, Ikumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634478/
https://www.ncbi.nlm.nih.gov/pubmed/28993647
http://dx.doi.org/10.1038/s41598-017-12828-z