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Usefulness of kidney slices for functional analysis of apical reabsorptive transporters
Kidney plays a key role in the elimination and reabsorption of drugs and nutrients, however in vitro methods to evaluate renal disposition are limited. In the present study, we investigated usefulness of isolated kidney slice, which had been used for transport only at basolateral membrane of tubular...
Autores principales: | Arakawa, Hiroshi, Washio, Ikumi, Matsuoka, Natsumi, Kubo, Hikaru, Staub, Angelina Yukiko, Nakamichi, Noritaka, Ishiguro, Naoki, Kato, Yukio, Nakanishi, Takeo, Tamai, Ikumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634478/ https://www.ncbi.nlm.nih.gov/pubmed/28993647 http://dx.doi.org/10.1038/s41598-017-12828-z |
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