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Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung

GW182 (also known asTNRC6) family members are critically involved in the final effector phase of miRNA-mediated mRNA repression. The three mammalian paralogs, TNRC6a, b and c, are thought to be redundant based on Argonaute (Ago) binding, tethering assays, and RNAi silencing of individual members in...

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Detalles Bibliográficos
Autores principales: Guo, Hua, Kazadaeva, Yana, Ortega, Fabian E., Manjunath, Narasimaswamy, Desai, Tushar J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634525/
https://www.ncbi.nlm.nih.gov/pubmed/28811219
http://dx.doi.org/10.1016/j.ydbio.2017.07.018