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Effects of AAV-mediated knockdown of nNOS and GPx-1 gene expression in rat hippocampus after traumatic brain injury

Virally mediated RNA interference (RNAi) to knock down injury-induced genes could improve functional outcome after traumatic brain injury (TBI); however, little is known about the consequences of gene knockdown on downstream cell signaling pathways and how RNAi influences neurodegeneration and behav...

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Detalles Bibliográficos
Autores principales: Boone, Deborah R., Leek, Jeanna M., Falduto, Michael T., Torres, Karen E. O., Sell, Stacy L., Parsley, Margaret A., Cowart, Jeremy C., Uchida, Tatsuo, Micci, Maria-Adelaide, DeWitt, Douglas S., Prough, Donald S., Hellmich, Helen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634593/
https://www.ncbi.nlm.nih.gov/pubmed/29016640
http://dx.doi.org/10.1371/journal.pone.0185943