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Protein-protein interactions in paralogues: Electrostatics modulates specificity on a conserved steric scaffold

An improved knowledge of protein-protein interactions is essential for better understanding of metabolic and signaling networks, and cellular function. Progress tends to be based on structure determination and predictions using known structures, along with computational methods based on evolutionary...

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Detalles Bibliográficos
Autores principales: Ivanov, Stefan M., Cawley, Andrew, Huber, Roland G., Bond, Peter J., Warwicker, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634604/
https://www.ncbi.nlm.nih.gov/pubmed/29016650
http://dx.doi.org/10.1371/journal.pone.0185928