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Mitochondrial Dysfunction in Chemotherapy-Induced Peripheral Neuropathy (CIPN)

The mitochondrial dysfunction has a critical role in several disorders including chemotherapy-induced peripheral neuropathies (CIPN). This is due to a related dysregulation of pathways involving calcium signalling, reactive oxygen species and apoptosis. Vincristine is able to affect calcium movement...

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Detalles Bibliográficos
Autores principales: Canta, Annalisa, Pozzi, Eleonora, Carozzi, Valentina Alda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634687/
https://www.ncbi.nlm.nih.gov/pubmed/29056658
http://dx.doi.org/10.3390/toxics3020198