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Live and Let Die: Roles of Autophagy in Cadmium Nephrotoxicity

The transition metal ion cadmium (Cd(2+)) is a significant environmental contaminant. With a biological half-life of ~20 years, Cd(2+) accumulates in the kidney cortex, where it particularly damages proximal tubule (PT) cells and can result in renal fibrosis, failure, or cancer. Because death repres...

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Detalles Bibliográficos
Autores principales: Thévenod, Frank, Lee, Wing-Kee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634690/
https://www.ncbi.nlm.nih.gov/pubmed/29056654
http://dx.doi.org/10.3390/toxics3020130