Cargando…

Live and Let Die: Roles of Autophagy in Cadmium Nephrotoxicity

The transition metal ion cadmium (Cd(2+)) is a significant environmental contaminant. With a biological half-life of ~20 years, Cd(2+) accumulates in the kidney cortex, where it particularly damages proximal tubule (PT) cells and can result in renal fibrosis, failure, or cancer. Because death repres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thévenod, Frank, Lee, Wing-Kee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634690/ https://www.ncbi.nlm.nih.gov/pubmed/29056654 http://dx.doi.org/10.3390/toxics3020130

Ejemplares similares

Renal hypoxia–HIF–PHD–EPO signaling in transition metal nephrotoxicity: friend or foe?
por: Thévenod, Frank, et al.
Publicado: (2022)

Iron and Cadmium Entry Into Renal Mitochondria: Physiological and Toxicological Implications
por: Thévenod, Frank, et al.
Publicado: (2020)

Corrigendum: Iron and Cadmium Entry Into Renal Mitochondria: Physiological and Toxicological Implications
por: Thévenod, Frank, et al.
Publicado: (2021)

Live and let die /
por: Fleming, Ian, 1908-1964
Publicado: (2002)

Granules live and let die
por: Bashyam, Hema
Publicado: (2008)

Cadmium Transporters in the Kidney and Cadmium-Induced Nephrotoxicity
por: Yang, Hong, et al.
Publicado: (2015)

Bcl-2: Live and let die
por: Putz, Eva Maria, et al.
Publicado: (2012)

Teaching an old dog new tricks: reactivated developmental signaling pathways regulate ABCB1 and chemoresistance in cancer
por: Lee, Wing-Kee, et al.
Publicado: (2021)

Cadmium and Lead Exposure, Nephrotoxicity, and Mortality
por: Satarug, Soisungwan, et al.
Publicado: (2020)

Systems biology of death receptor networks: live and let die
por: Lavrik, I N
Publicado: (2014)

Cadmium induces Wnt signaling to upregulate proliferation and survival genes in sub-confluent kidney proximal tubule cells
por: Chakraborty, Prabir K, et al.
Publicado: (2010)

Intracellular staphylococcus aureus: Live-in and let die
por: Fraunholz, Martin, et al.
Publicado: (2012)

Live and let die: asymmetric dimethylarginine and septic shock
por: Böger, Rainer H
Publicado: (2006)

To live or let die – complexity within the E2F1 pathway
por: Poppy Roworth, A, et al.
Publicado: (2015)

Role of hepcidin in oxidative stress and cell death of cultured mouse renal collecting duct cells: protection against iron and sensitization to cadmium
por: Probst, Stephanie, et al.
Publicado: (2021)

Killing and letting die
Publicado: (1980)

Cadmium Handling, Toxicity and Molecular Targets Involved during Pregnancy: Lessons from Experimental Models
por: Jacobo-Estrada, Tania, et al.
Publicado: (2017)

Cadmium Complexed with β2-Microglubulin, Albumin and Lipocalin-2 rather than Metallothionein Cause Megalin:Cubilin Dependent Toxicity of the Renal Proximal Tubule
por: Fels, Johannes, et al.
Publicado: (2019)

Biologic indicators of cadmium nephrotoxicity in persons with low-level cadmium exposure.
por: Nogawa, K
Publicado: (1984)

Urinary metallothionein as an indicator of cadmium body burden and of cadmium-induced nephrotoxicity.
por: Shaikh, Z A, et al.
Publicado: (1984)

Live or let die: oestrogen regulation of survival signalling in endocrine response
por: Butt, Alison J, et al.
Publicado: (2007)

Mitochondrial calcium uniporter, MiRNA and cancer: Live and let die
por: Marchi, Saverio, et al.
Publicado: (2013)

Live and let die: signaling AKTivation and UPRegulation dynamics in SARS-CoVs infection and cancer
por: Suaya, Mariana, et al.
Publicado: (2022)

Autophagy in Cisplatin Nephrotoxicity during Cancer Therapy
por: Hu, Xiaoru, et al.
Publicado: (2021)

A Comparison of the Nephrotoxicity of Low Doses of Cadmium and Lead
por: Satarug, Soisungwan, et al.
Publicado: (2020)

Increased Endocytosis of Cadmium-Metallothionein through the 24p3 Receptor in an In Vivo Model with Reduced Proximal Tubular Activity
por: Zavala-Guevara, Itzel Pamela, et al.
Publicado: (2021)

Die and let live: harnessing BikDD to combat breast cancer stem cells
por: Giuliano, Mario, et al.
Publicado: (2012)

Role of Autophagy in Cadmium-Induced Hepatotoxicity and Liver Diseases
por: Niture, Suryakant, et al.
Publicado: (2021)

Evaluation of cystatin C as an early biomarker of cadmium nephrotoxicity in the rat
por: Prozialeck, Walter C., et al.
Publicado: (2015)

Royal jelly attenuates cadmium-induced nephrotoxicity in male mice
por: Almeer, Rafa S., et al.
Publicado: (2019)

In vitro nephrotoxicity and anticancer potency of newly synthesized cadmium complexes
por: Abyar, Selda, et al.
Publicado: (2019)

A microbiologist can't let their sourdough die
por: Wettstadt, Sarah
Publicado: (2022)

Human kidney organoids model the tacrolimus nephrotoxicity and elucidate the role of autophagy
por: Kim, Jin Won, et al.
Publicado: (2021)

Live and Let Die? Life Cycle Human Health Impacts from the Use of Tire Studs
por: Furberg, Anna, et al.
Publicado: (2018)

Honokiol Antagonizes Cadmium-Induced Nephrotoxicity in Quail by Alleviating Autophagy Dysfunction, Apoptosis and Mitochondrial UPR Inhibition with Its Antioxidant Properties
por: Zhang, Kanglei, et al.
Publicado: (2022)

New approaches for detecting thresholds of human nephrotoxicity using cadmium as an example.
por: Mueller, P W, et al.
Publicado: (1998)

Combining Patulin with Cadmium Induces Enhanced Hepatotoxicity and Nephrotoxicity In Vitro and In Vivo
por: Cui, Jinling, et al.
Publicado: (2021)

Subcellular targets of cadmium nephrotoxicity: cadmium binding to renal membrane proteins in animals with or without protective metallothionein synthesis.
por: Nordberg, G F, et al.
Publicado: (1994)

Annotations: "Let Him Die."—Hospitals at Home &c.
Publicado: (1888)

Inverse Regulation of Lipocalin-2/24p3 Receptor/SLC22A17 and Lipocalin-2 Expression by Tonicity, NFAT5/TonEBP and Arginine Vasopressin in Mouse Cortical Collecting Duct Cells mCCD(cl.1): Implications for Osmotolerance
por: Probst, Stephanie, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_f3nn33o3rk0akmlabcrd1je3s8