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Neurotoxic Effects of Platinum Compounds: Studies in vivo on Intracellular Calcium Homeostasis in the Immature Central Nervous System

Platinum compounds cause significant clinical neurotoxicity. Several studies highlight neurological complications especially in paediatric oncology patients with Central Nervous System (CNS) and non-CNS malignancies. To understand the toxicity mechanisms of platinum drugs at cellular and molecular l...

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Detalles Bibliográficos
Autores principales: Bernocchi, Graziella, Fanizzi, Francesco P., De Pascali, Sandra A., Piccolini, Valeria M., Gasperini, Caterina, Insolia, Violetta, Bottone, Maria Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634691/
https://www.ncbi.nlm.nih.gov/pubmed/29056659
http://dx.doi.org/10.3390/toxics3020224