Cargando…

Quantification of mitochondrial DNA copy number in suspected cancer patients by a well optimized ddPCR method

Changes in mitochondrial DNA (mtDNA) content is a useful clinical biomarker for various diseases, however results are controversial as several analytical factors can affect measurement of mtDNA. MtDNA is often quantified by taking ratio between a target mitochondrial gene and a reference nuclear gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Memon, Ashfaque A., Zöller, Bengt, Hedelius, Anna, Wang, Xiao, Stenman, Emelie, Sundquist, Jan, Sundquist, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634817/
https://www.ncbi.nlm.nih.gov/pubmed/29021970
http://dx.doi.org/10.1016/j.bdq.2017.08.001