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Quantification of mitochondrial DNA copy number in suspected cancer patients by a well optimized ddPCR method
Changes in mitochondrial DNA (mtDNA) content is a useful clinical biomarker for various diseases, however results are controversial as several analytical factors can affect measurement of mtDNA. MtDNA is often quantified by taking ratio between a target mitochondrial gene and a reference nuclear gen...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634817/ https://www.ncbi.nlm.nih.gov/pubmed/29021970 http://dx.doi.org/10.1016/j.bdq.2017.08.001 |